Reactions of Carbonyls-Aldehyde/Ketone Analysis: Introduction: The carbonyl group is a rich source of many important reactions in organic chemistry‚ with two fundamental properties that are primarily responsible for its diverse chemistry. The first is the polarization of the. Carbon-oxygen pi bond‚ owing to the relatively high electro negativity. The second property of a carbonyl function is to increase the acidity of the alpha-hydrogen atoms‚ which are the hydrogen’s
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Procedure: The experimental laboratory procedures were divided into two categories. First the formation of phenylmagnesium bromide‚ and second the reaction of the phenylmagnesium bromide with the carbonyl compound. However‚ before any of this could be done‚ the refluxing apparatus for the Grignard reaction was to be flame dried until no moisture remained inside because any water would cause the reagent to decompose and an alkane to form. The reaction would subsequently fail. Drierite was placed
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Topic 8a – Carbonyl compounds Revision Notes 1. Introduction • Aldehydes and ketones are carbonyl compounds • They contain the carbonyl group C=O • The functional group in aldehydes is –CHO on the end of a chain e.g. ethanal CH3CHO • The functional group in ketones is C=O not at the end of a chain e.g. propanone CH3COCH3 2. AS Recap • Primary alcohols are oxidised by acidified potassium dichromate. An aldehyde is produced first and this can be further oxidised
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Functional Group Analysis: Carbonyl Compounds‚ Oxidizable Carbonyl Compounds and Acidic Compounds Christian Paul L. Ramos Institute of Chemistry‚ University of the Philippines‚ Diliman‚ Quezon City 1101 Philippines Date Performed: August 24‚ 2012; Date Submitted: September 19‚ 2012 Results and Discussion Aldehydes and ketones both contain the carbonyl group – a group in which a carbon atom has a double bond to oxygen. The carbonyl group in aldehydes is bonded to at least one
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INTRODUCTION The purpose of this experiment is to synthesize trans-9-(2-phenylethenyl) anthracene from benzyltriphenylphosphonium chloride and 9-anthraldehyde through the reaction mechanism recognized as the Wittig Reaction. The Wittig Reaction allows the chemist to synthesize phosphoranes in the lab with relative ease. A more recent and inexpensive version of the reaction is the Wittig-Horner reaction (1). ABSTRACT Georg Wittig was a German chemist and Nobel Prize winner in 1979 for the Wittig
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reactions. It belongs to the reactions of the enolate derived from a carbonyl group with an electrophilic carbon such as Aldol‚ Claisen‚ Michael reaction and alkylation of metal enolates [6-9].The acylation reaction as well as above other reactions of enolates has serious limitations to be overcome. In these reactions‚ a strong base NaOH is needed to transform the carbonyl compounds into their anion forms. Generally‚ the carbonyl compounds such as ketone and aldehyde have high pKa values (pKa ~ 20)
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Organometallic preparation and addition to carbonyls‚ Wittig reagent preparation and Wittig rxn‚ Wolff‚ H-based nucleophile carbonyl reduction‚ imine formation‚ reductive amination (rxn only)‚ ketal/acetal formation‚ dithiane chemistry (rxn only)‚ alpha-bromination of ketones‚ -COOH properties (the trends on HW4)‚ Fischer‚ acidic/basic hydrolysis of esters/amides/nitriles‚ CH2N2‚ acid chloride formation (rxn only)‚ acid chloride rxns with esters and amides. 2 Rxn of carboxyllic acid derivatives
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any enol that formed quickly reacted with the strong base to form the enolate ion. Therefore‚ the generation of the enolate drove this reaction to completion (Le Chatelier’s principle). Being a very strong nucleophile‚ this enolate attacked the carbonyl of benzaldehyde and formed an alkoxide ion. This alkoxide ion abstracted a proton from water to form a beta keto alcohol which then tautermerizes to an enol. This enol reacted with base to form yet another enolate. Finally‚ the enolate lost a hydroxide
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Tetraphenylcyclopentadienone In this laboratory experiment a synthesis was performed through several separate steps. The purpose of the experiment was to synthesize tetraphenylcyclopentadienone from benzaldehyde and to run reactions on carbonyl containing compounds. There was a total of three steps that led up to the synthesis of the final product‚ tetraphenylcyclopentadienone. The first step of the experiment was the condensation of benzaldehyde to yield benzoin. Thiamine catalyst
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Vidallon‚ Mark Louis P. Date Performed: February 20‚ 2012 CHEM44.1 2L Date Submitted: March 12‚ 2012 MIXED-ALDOL CONDENSATION Synthesis of Cinnamaldehyde I. Introduction Cinnamaldehyde‚ cinnamic aldehyde or 3-phenyl-2-propenal is the major constituent of cinnamon oil‚ extracted from several species of Cinnamomum (C. verum‚ C. burmanii‚ C. cassia)‚ under the family Lauraceae‚ a group of evergreen trees. Cinnamon bark (particularly C. verum) yields 0.4-0.8% oil‚ which contains 60-80% cinnamaldehyde
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