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Submitted by ibrahim00 on March 20, 2006
Category: Technology
Words: 7177 | Pages: 29
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ISIS Sustainable Science Audit #2
Xenotransplantation:
How Bad Science and Big Business Put the World at Risk
from Viral Pandemics
by Mae-Wan Ho and Joe Cummins
________________________________________
Summary
Xenotransplantation - the transplant of animal organs into human beings - is a multi-billion dollar business venture built on the
anticipated sale of patented techniques and organs, as well as drugs to overcome organ-rejection (1). It has received strong criticism
and opposition from scientists warning of the risks of new viruses crossing from animal organs to human subjects and from there to
infect the population at large. But regulators are adopting a permissive attitude for clinical trials to go ahead. Scientific reports of virus
crossing from pig to human cells (2) and of viral infections in humans subjects transplanted with baboon livers (3) are being ignored or
dismissed, while inconclusive, widely faulted papers are taken as evidence that no viruses are found in xenotransplant patients (4).
This audit exposes the shoddy science that puts the world at risk of viral pandemics for the sake of corporate profit, and concludes
that xenotranplantation should not be allowed to continue in any form. Instead, effort should be devoted to developing safer, more
sustainable and affordable alternatives that are already showing promise and will be more likely to benefit society as a whole in the
industrialized west as well as in the Third World.
Key words: transgenic pigs, hyperacute rejection, xenozoonosis, endogenous retroviruses, xenotropism, viral infections,
recombinant viruses, PERV, pig HEV, baboon endogenous virus, simian foamy virus.
A multi-billion dollar business venture
Xenotransplantation - the transplant of organs or tissues between species – has...
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