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Technical Review Article

Submitted by stacymum on April 9, 2008

Category: Technology
Words: 1397 | Pages: 6
Views: 59
Popularity Rank: 104,369
Average Member Grade: N/A (Add a Comment / Grade this Paper)

Title: An algorithm to estimate the importance of bacterial acquisition routes in hospital settings.
Authors: M. C. J. Bootsma, M. J. M. Bonten, S. Nijssen, A. C. Fluit, and O. Diekmann.

Introduction
The significant increase in antibiotic resistance amongst pathogens is making it very difficult to successfully treat infections, especially in intensive care units (ICU’s). Prevention of the spread of infection among patients within the hospitals is fast becoming amongst the most important methods for controlling infections. This requires the identification of the different acquisition routes, that is, routes by which bacterial colonization occurs. In this article, the authors analyzed the relative importance of various bacterial acquisition routes that resulted in colonization of the bacteria using data from individual patients.[1] This article was chosen because of the impact it can have on the healthcare system if the knowledge obtained from the algorithm regarding the most prevalent colonization routes in hospitals can help in the preventing spread of infections. Also the ability of the algorithm to incorporate specific patient characteristics makes it both novel and appealing.

Core Evaluation
Hypothesis Development
In this article, the authors present an algorithm that can be used to quantitatively determine the likelihood of colonization occurring from different acquisition routes. This algorithm uses individual patient data regarding the duration of their stay in the ICU and specific characteristics which builds on previously proposed algorithms that only consider the number of patients colonized. The authors state that the algorithm is “a promising tool for disentangling the contributions of various acquisition routes on the basis of longitudinal data without requiring labor intensive and costly genotyping procedures”,[1] which shows that they believe that the algorithm can give reliable...

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