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open versus endoscopic lumbar pedicle screw fixation. Introduction: With
improved spinal instrumentation and surgical technique, the ...
Open Versus Endoscopic Lumbar Pedicle Screw Fixation. Introduction: With
improved spinal instrumentation and surgical technique, the ...
Submitted by y365124 on March 26, 2008
Category: Science
Words: 4994 | Pages: 20
Views: 67
Popularity Rank: 108,408
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Introduction:
With improved spinal instrumentation and surgical technique, the non-union rate for spinal fusion has dramatically declined in recent years. However, pseudoarthrosis remains common in certain patient populations such as the elderly, those who smoke and drink, those with metastatic and metabolic disorders, and those who do not comply with post-operative recommendations. In these populations and others, the non-union rate can be as high as 35% (1). In addition to non-union, complications associated with the harvest of autogenous bone such as donor site morbidity, blood loss, and increased operative time, has prompted the search for suitable alternatives (2,3). In addition to these problems, many spinal fusion surgeries are lengthy procedures that involve a relatively large surgical field, and are associated with a great deal of morbidity and a long hospital stay.
Recently, many new bone graft substitutes are being designed to incorporate or mimic one or more of the bone-forming components of autogenous bone to prevent the morbidity of the bone graft donor site. This is often achieved by combining a purified, recombinant form of an osteoinductive protein with an osteoconductive scaffold or matrix to attract, simulate, and support the formation of new bone by host osteogenic cells (1, 4-6). A number of spinal researchers and surgeons have applied this technology to spinal fusion with great success (1,4-19). As well as the development of the bone graft substitutes, improved spinal instrumentation and endoscopic surgical technique are also successfully used in spinal surgery (8, 20-27). By reducing the size of the incision, the surgeon reduces the iatrogenic trauma imparted on surrounding tissues, the risk of infection and the healing time.
In an attempt to eventually reduce the size of incision and dissection, and reduce the amount of bed rest each patient must endure, this study was designed to test novel graft substitute...
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