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Nitrix

Part A:
In 1998 the Nobel Prize for medicine was awarded to the men who discovered that nitric oxide acts as a signal in the cardiovascular system. Now the supplement company BSN is manufacturing a nutritional product called Nitrix, and are claiming that this product enhances the vasodilating properties of nitric oxide.

Nitrix is a nutritional supplement sold in tablet form, and each tablet consists of:
- 200mcg Vitamin B9 (folic acid)
- 3000mg L-Arginine Alpha Keto-Glutarate
- 1791mg CRTS2 (Controlled Release Technology & Support System) made up of:
o Methocel (Micro-Polymer Hydrophilic Ether Matrix)
o Phosphoplexx (Di-Calcium Phosphate, Di-Potassium Phosphate, Di-Sodium Phosphate)
o CEM3 (Creatine-Ethyl-Ester-Malate)
o L-Citrulline
o NAD (Nicotinamine Adenine Dinucleotide)
- Magnesium Stearate
- Stearic Acid
See Figure 1 in Appendix A for supplement label.

This product claims to function as a "vaso-muscular volumizer" when taken for an optimal cycle length of 12 weeks with a suggested cycle off length of 4 weeks. Users of this product under 200 pounds are recommended to take 3 tablets, 3 times per day on an empty stomach, every day. Users over 200 pounds are recommended to increase this dose to 4 tablets, 3 times daily. The company suggests that doses be taken upon rising, before lunch, and before dinner. It is also noted that glutamine supplements should not be taken at the same time as Nitrix as doing so may diminish its effects. Nitrix is sold at a price of $99.99 for 360 tablets, indicating that users under 200 pounds would get 40 days of use out of one bottle, while those over 200 pounds would get 30 days use.

The makers of Nitrix claim that this product supports maximum nitric oxide levels in skeletal muscles, which volumizes muscle tissue resulting in increased vascularity, tone and muscle hardness (2). This is because nitric oxide is involved in the dilation of blood vessels, which permits more blood to flow into tissues...