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The link between obesety and type II diabetes Diabetes is a devastating and potentially life threatening disease that affects thousands of Americans each year. The
Submitted by salteir on May 10, 2008
Category: Science
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Diabetes is a devastating and potentially life threatening disease that affects thousands of Americans each year. The fact of the matter is that although it impacts the lives of thousands of people, there still remain questions about the disease that need to be answered. One of the hot topics of today’s scientific research is whether or not there is a link between obesity and type II diabetes. Type II diabetes is a chronic metabolic condition that is caused by defects with the endogenous insulin. Insulin is a hormone produced by the pancreas that carries and transports the glucose from the blood into the cells for energy in amounts that allow the body to function properly (Lebovitz, 1999). This generally occurs because the body is not producing enough insulin to regulate the bloods glucose level (Lebovitz, 1999). Another cause can be that even if the pancreas is producing enough insulin, the cells do not respond properly to the insulin, causing the insulin to be inefficient (Lebovitz, 1999). A major problem of this disease is the resulting high glucose levels, which is a result of the ineffectiveness of the insulin; this may result in hyperglycemia, or high blood pressure, which can cause damage to numerous organs in the body (Lebovitz, 1999).
Type II diabetes has been continuously linked to the rising epidemic of obesity. Recently it has been found that the biggest factor that influences type II diabetes is visceral adipose tissue, which is the fat of the organs, resulting in the bulging of the stomach (Shulman, 2004; Sorisky, 2008). It is found to be that this type of adipose tissue is one of the biggest reasons for insulin resistance; people with Visceral adipose tissue have difficulties storing fat in cells in this area because the tissue can not expand in order to house all the extra calories, the adipogenic capacity with in this adipose tissue weakens which causes hypertrophied (increased) adipocytes (Sorisky, 2008).
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