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Life Transitions: Necrosis. LIFE TRANSITIONS: NECROSIS 1.0 Introduction
Death of cells in the animal body may either occur normally ...
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Submitted by Yaddles on May 10, 2008
Category: Science
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LIFE TRANSITIONS: NECROSIS
1.0 Introduction
Death of cells in the animal body may either occur normally or pathologically (caused by disease). There are three distinct modes of cell death, Necrobiosis, Apoptosis, and Necrosis. The first two are considered as a homeostatic (the ability or tendency of an organism or cell to maintain internal equilibrium by adjusting its physiological processes) mechanism of the body in controlling cell population, renewal of cells, and in the process of “improving” organs. Necrosis is the term used for the un-programmed death of tissue. Apoptosis and Necrobiosis are programmed cell-deaths. Necrosis is not reversible. The causes of Necrosis may be internal or external, and there are various types of Necrosis, some of which are:
• Coagulative Necrosis
• Avascular Necrosis
• Ischemic Necrosis
• Osteonecrosis
• Aseptic Necrosis
• Liquefactive Necrosis
• Caseous Necrosis
• Fat Necrosis
• Fibrinoid Necrosis
• Zenker Necrosis
• Gangrenous Necrosis
• Acral Necrosis
• Arteriolonecrosis
• Central Necrosis
2.0 Necrobiosis: Group Culling
Necrobiosis is programmed cell death. It is the death of a part by molecular disintegration and without loss of continuity, as in the processes of degeneration and atrophy. This is, however, a normal series of events in a cell leading it to termination. Notably, cancer cells avoid this process.
Necrobiosis occurs in adults as part of a normal cell renewal. For example:
In Blood:
Red blood cell turnover process starts when the haemoglobin molecules begin to precipitate and new haemoglobin cannot be synthesised. The marrow, to replace the dying red blood cells, produces new red blood cells with new haemoglobin.
In the Intestines:
The cells which are...
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