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diabetes II Running Head: Type II Diabetes Proposal for a Research Grant on Type II Diabetes One of the most serious (and misunderstood) diseases that affects our
Submitted by jennuhxo on May 16, 2005
Category: Miscellaneous
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Diabetes
Diabetes mellitus is a condition in which the pancreas no longer produces insulin or when cells stop responding to the insulin that is produced so that glucose in the blood cannot be absorbed into the cells of the body. Diabetes is classified into two categories; Type 1. Approximately 14 million people in the United States alone have some type of Diabetes that is about 5% of the population. In the United States, Diabetes causes nearly 200,000 deaths a year.
The human pancreas has two main functions: to produce pancreatic endorphin hormones, which help regulate many aspects of our metabolism and to produce pancreatic digestive enzymes. Pancreatic production of insulin, somatostatin, gastrin, and glucagon plays an important role in maintaining sugar and salt balance in our bodies and therefore any problem in the production or regulation of these hormones will manifest itself with problems with blood sugar and fluid / salt imbalances.
Type 1 and Type 2 diabetes are two diseases that can be compared and contrasted according to their causes. Type 1 diabetes is similar to type 2 diabetes in that they are genetic diseases. Recently, researchers have been attempting to locate the genes for diabetes. As a part of the genome project in which researchers around the world are attempting to map the entire gene structure of all the human chromosomes, they have isolated 18 genes that appear to be involved in the production of type 1 diabetes. Not all of these genes have equal potency. Two of them appear to be most potent, some others are least potent, and others are simply auxiliary or helper genes that seem to have the similar effect in the process. There are also genes, which are protective so that one might inherit the genes for diabetes, but if the person also inherits the protective gene, they wouldn't develop the disease. Thus, development of the disease is not 100% in those who have inherited the genes for the diseases. Those...
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