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Chimera & Mosaicism Chimera according to the genome glossary is an organism which possesses cells or tissues with a different genotype. This can be caused due to
chimera Human chimeras were once thought to be so rare as to be just a curiosity. But there's a little bit of someone else in all of us, says Claire Ainsworth, and
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this is what the use of genetic engineering brings to the world. "In Greek myth, an chimera was a part lion, part goat, part dragon that lived in Lycia; in real life,
was captured by Bellerophon at the water of his fountain and was ridden by him when he killed Chimera. Bellerophon showed disrespect to the Gods as he attempted to
Submitted by geyonce85 on November 29, 2007
Category: Science
Words: 2378 | Pages: 10
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Human chimeras were once thought to be so rare as to be just a curiosity.
But there's a little bit of someone else in all of us, says Claire
Ainsworth, and sometimes much more...
EXPLAIN this. You are a doctor and one of your patients, a 52-year- old
woman, comes to see you, very upset. Tests have revealed something
unbelievable about two of her three grown-up sons. Although
she conceived them naturally with her husband, who is definitely
their father, the tests say she isn't their biological mother.
Somehow she has given birth to somebody else's children.
This isn't a trick question - it's a genuine case that Margot Kruskall, a
doctor at the Beth Israel Deaconess Medical Center in Boston,
Massachusetts, was faced with five years ago. The patient, who we will
call Jane, needed a kidney transplant, and so her family underwent blood
tests to see if any of them would make a suitable donor. When the results
came back, Jane was hoping for good news.
Instead she received a hammer blow. The letter told her outright that
two of her three sons could not be hers. What was going on?
It took Kruskall and her team two years to crack the riddle. In the end
they discovered that Jane is a chimera, a mixture of two individuals -
non-identical twin sisters - who fused in the womb and grew into a single
body. Some parts of her are derived from one twin, others from the other.
It seems bizarre that this can happen at all, but Jane's is not an
isolated case. Around 30 similar instances of chimerism have been
reported, and there are probably many more out there who will never
discover their unusual origins.
While cases like Jane's are the extreme, researchers now think that
there's a little bit of chimera in all of us, and what was once seen
as a biological...
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