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Benign prostatic hyperplasia. Benign ... Benign prostatic hyperplasia symptoms
are classified as obstructive or irritative. Obstructive ...
... and loving this world. Benign prostatic hyperplasia (BPH) is a condition
that affects the prostate gland in men. The prostate is a ...
... their respective indications is as follows: 1. Clinical Development a. GnRH Antagonist –
endometriosis and benign prostatic hyperplasia b. CRF1 Antagonsit ...
... medicines to help treat high blood pressure, congestive heart failure, elevated
cholesterol levels, osteoporosis, benign prostatic hyperplasia, arthritis, pain ...
... Another trial tried to determine if a saw palmetto plant extract reduced the symptoms
associated with benign prostatic hyperplasia, but showed now definitive ...
Submitted by Tpressano on June 10, 2008
Category: Science
Words: 1655 | Pages: 7
Views: 38
Popularity Rank: 116,027
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Benign prostatic hyperplasia (BPH) also known as nodular hyperplasia, benign prostatic hypertrophy (technically a misnomer) or benign enlargement of the prostate (BEP) refers to the increase in size of the prostate in middle-aged and elderly men. To be accurate, the process is one of hyperplasia rather than hypertrophy, but the nomenclature is often interchangeable, even amongst urologists. It is characterized by hyperplasia of prostatic stromal and epithelial cells, resulting in the formation of large, fairly discrete nodules in the periurethral region of the prostate. When sufficiently large, the nodules compress the urethral canal to cause partial, or sometimes virtually complete, obstruction of the urethra which interferes the normal flow of urine. It leads to symptoms of urinary hesitancy, frequent urination, increased risk of urinary tract infections and urinary retention. Although prostate specific antigen levels may be elevated in these patients because of increased organ volume and inflammation due to urinary tract infections, BPH is not considered to be a premalignant lesion. Adenomatous prostatic growth is believed to begin at approximately age 30 years. An estimated 50% of men have histologic evidence of BPH by age 50 years and 75% by age 80 years. In 40-50% of these patients, BPH becomes clinically significant.
Benign prostatic hyperplasia symptoms are classified as obstructive or irritative. Obstructive symptoms include hesitancy, intermittency, incomplete voiding, weak urinary stream, and straining. Irritative symptoms include frequency of urination, which is called nocturia when occurring at night time, and urgency (compelling need to void that can not be deferred). These obstructive and irritative symptoms are evaluated using the International Prostate Symptom Score (IPSS) questionnaire, designed to assess the severity of BPH. BPH can be a progressive disease, especially if left untreated. Incomplete voiding results in stasis of bacteria...
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